Physical Modeling of Chemical Exchange Saturation Transfer Imaging
نویسندگان
چکیده
منابع مشابه
Analytical determination of the chemical exchange saturation transfer (CEST) contrast in molecular magnetic resonance imaging
Magnetic resonance based on molecular imaging allows tracing contrast agents thereby facilitating early diagnosis of diseases in a non-invasive fashion that enhances the soft tissue with high spatial resolution. Recently, the exchange of protons between the contrast agent and water, known as the chemical exchange saturation transfer (CEST) effect, has been measured by applying a suitable pulse ...
متن کاملERRATUM: Uniform magnetization transfer in chemical exchange saturation transfer magnetic resonance imaging
The baseline and the magnetization transfer (MT) line were omitted from Figure 1a during the typesetting of the Article. The correct Figure 1 appears below.
متن کاملUniform magnetization transfer in chemical exchange saturation transfer magnetic resonance imaging
The development of chemical exchange saturation transfer (CEST) has led to the establishment of new contrast mechanisms in magnetic resonance imaging, which serve as enablers for advanced molecular imaging strategies. Macromolecules in tissues and organs often give rise to broad and asymmetric exchange effects, called magnetization transfer (MT) effects, which can mask the CEST contrast of inte...
متن کاملIn vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.
Glioblastoma multiforme (GBM), which account for more than 50% of all gliomas, is among the deadliest of all human cancers. Given the dismal prognosis of GBM, it would be advantageous to identify early biomarkers of a response to therapy to avoid continuing ineffective treatments and to initiate other therapeutic strategies. The present in vivo longitudinal study in an orthotopic mouse model de...
متن کاملMolecular imaging of tumors and metastases using chemical exchange saturation transfer (CEST) MRI.
The two glucose analogs 2-deoxy-D-glucose (2-DG) and 2-fluoro-2-deoxy-D-glucose (FDG) are preferentially taken up by cancer cells, undergo phosphorylation and accumulate in the cells. Owing to their exchangeable protons on their hydroxyl residues they exhibit significant chemical exchange saturation transfer (CEST) effect in MRI. Here we report CEST-MRI on mice bearing orthotopic mammary tumors...
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ژورنال
عنوان ژورنال: Progress in Medical Physics
سال: 2017
ISSN: 2508-4445,2508-4453
DOI: 10.14316/pmp.2017.28.4.135